2025 ICD-10-CM Diagnosis Code C74

Malignant neoplasm of adrenal gland

  • C74 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2025 edition of ICD-10-CM C74 became effective on October 1, 2024.
  • This is the American ICD-10-CM version of C74 – other international versions of ICD-10 C74 may differ.

The following code(s) above C74 contain annotation back-references

 that may be applicable to C74:

Clinical Information

  • A number of disorders can affect the adrenal glands, including several types of cancer. Adrenal gland cancers are uncommon. They include
    • adrenocortical carcinoma – cancer in the outer part of the gland
    • neuroblastoma, a type of childhood cancer
    • pheochromocytoma
    most adrenal gland tumors are non-cancerous adenomas that usually do not cause symptoms and may not require treatment.symptoms of adrenal gland cancer depend on the type of cancer you have. Treatments may include surgery, chemotherapy, or radiation therapy.
  • A primary or metastatic malignant neoplasm affecting the adrenal gland.
  • Cancer that forms in the tissues of the adrenal glands (two glands located just above the kidneys). The adrenal glands make hormones that control heart rate, blood pressure, and other important body functions. Adrenal cancer that starts in the outside layer of the adrenal gland is called adrenocortical carcinoma. Adrenal cancer that starts in the center of the adrenal gland is called malignant pheochromocytoma.

Code History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): No change

Code annotations containing back-references to C74:

  • Type 1 Excludes: C75
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