2025 ICD-10-CM Diagnosis Code C81.1

by

Nodular sclerosis Hodgkin lymphoma

  • C81.1 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2025 edition of ICD-10-CM C81.1 became effective on October 1, 2024.
  • This is the American ICD-10-CM version of C81.1 – other international versions of ICD-10 C81.1 may differ.

Applicable To

  • Nodular sclerosis classical Hodgkin lymphoma

The following code(s) above C81.1 contain annotation back-references

 that may be applicable to C81.1:

  • C00-D49  Neoplasms
  • C81-C96  Malignant neoplasms of lymphoid, hematopoietic and related tissue
  • C81  Hodgkin lymphoma

Clinical Information

  • A subtype of classical hodgkin lymphoma characterized by collagen bands surrounding lymphoid nodules. The lymphoid nodules contain lacunar and reed-sternberg cells. Mediastinal involvement occurs in 80% of patients. The prognosis of nodular sclerosis hodgkin lymphoma is slightly better than that of mixed cellularity or lymphocyte depleted subtype. (who, 2001)

Code History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): Revised code
    • New description: Nodular sclerosis Hodgkin lymphoma
    • 2016 description: Nodular sclerosis classical Hodgkin lymphoma
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): No change

Diagnosis Index entries containing back-references to C81.1:

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