2025 ICD-10-CM Diagnosis Code C82

Follicular lymphoma

  • C82 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2025 edition of ICD-10-CM C82 became effective on October 1, 2024.
  • This is the American ICD-10-CM version of C82 – other international versions of ICD-10 C82 may differ.

Type 1 Excludes

  • mature T/NK-cell lymphomas (C84.-)
  • personal history of non-Hodgkin lymphoma (Z85.72)

Includes

  • follicular lymphoma with or without diffuse areas

The following code(s) above C82 contain annotation back-references

 that may be applicable to C82:

  • C00-D49  Neoplasms
  • C81-C96  Malignant neoplasms of lymphoid, hematopoietic and related tissue

Clinical Information

  • A neoplasm of follicle centre b cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-hodgkin lymphomas in the United States And 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as grade 1, grade 2, and grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the bcl-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from who, 2001).
  • A neoplasm of lymphoid cells which has at least a partial follicular pattern.
  • A type of b-cell non-hodgkin lymphoma (cancer of the immune system) that is usually indolent (slow-growing). The tumor cells grow as groups to form nodules. There are several subtypes of follicular lymphoma.
  • Malignant lymphoma in which the lymphomatous cells are clustered into identifiable nodules within the lymph nodes. The nodules resemble to some extent the germinal center of lymph node follicles and most likely represent neoplastic proliferation of lymph node-derived follicular center b-lymphocytes.

Code History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): No change
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