2025 ICD-10-CM Diagnosis Code C83.8

by

Other non-follicular lymphoma

  • C83.8 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2025 edition of ICD-10-CM C83.8 became effective on October 1, 2024.
  • This is the American ICD-10-CM version of C83.8 – other international versions of ICD-10 C83.8 may differ.

Applicable To

  • Intravascular large B-cell lymphoma
  • Lymphoid granulomatosis
  • Primary effusion B-cell lymphoma

Type 1 Excludes

  • mediastinal (thymic) large B-cell lymphoma (C85.2-)
  • T-cell rich B-cell lymphoma (C83.3-)

The following code(s) above C83.8 contain annotation back-references

 that may be applicable to C83.8:

  • C00-D49  Neoplasms
  • C81-C96  Malignant neoplasms of lymphoid, hematopoietic and related tissue
  • C83  Non-follicular lymphoma

Clinical Information

  • A neoplastic lymphoproliferative process characterized by an angiocentric arrangement of the tumor cells which is associated with angiodestruction. It includes lymphomatoid granulomatosis which is a lymphoproliferative lesion derived from mature b-lymphocytes and cases of extranodal nk/t-cell lymphomas of nasal type.
  • A rare extranodal b-cell non-hodgkin lymphoma, characterized by the presence of lymphoma cells exclusively in the lumina of small vessels, particularly capillaries. This is an extremely aggressive lymphoma which responds poorly to chemotherapy. (who, 2001)
  • An angiocentric and angiodestructive lymphoproliferative disease involving extranodal sites, comprised of epstein-barr virus (ebv)-positive b-cells admixed with reactive t-cells. Incidence is higher among adult males; patients with a history of immunodeficiency are at increased risk. The most common site of involvement is the lung; other common sites include brain, kidney, liver, and skin. Morphologically, three grades are recognized: grade i, ii, and iii. Grade iii lymphomatoid granulomatosis should be approached clinically as a subtype of diffuse large b-cell lymphoma.
  • An angiocentric and angiodestructive lymphoproliferative disorder primarily involving the lungs. It is caused by an epstein-barr virus-induced transformation of the b-cells, in a t-cell rich environment. Clinically and pathologically it resembles extranodal nk-t-cell lymphoma.
  • Destructive growth of lymph cells, usually involving the lungs, skin, kidneys, and central nervous system. Grades i and ii are not considered cancerous, but grade iii is considered a lymphoma.

Code History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): No change

Diagnosis Index entries containing back-references to C83.8:

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