2025 ICD-10-CM Diagnosis Code C86.1

Hepatosplenic T-cell lymphoma

  • C86.1 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • ICD-10-CM C86.1 is a new 2025 ICD-10-CM code that became effective on October 1, 2024.
  • This is the American ICD-10-CM version of C86.1 – other international versions of ICD-10 C86.1 may differ.

Applicable To

  • Alpha-beta and gamma delta types

The following code(s) above C86.1 contain annotation back-references

 that may be applicable to C86.1:

  • C00-D49  Neoplasms
  • C81-C96  Malignant neoplasms of lymphoid, hematopoietic and related tissue
  • C86  Other specified types of T/NK-cell lymphoma

Approximate Synonyms

  • Lymphoma, hepatosplenic t-cell

Clinical Information

  • An extranodal, mature t-cell non-hodgkin lymphoma that originates from cytotoxic t-cells, usually of gamma/delta t-cell type. It is characterized by the presence of medium-size neoplastic lymphocytes infiltrating the hepatic sinusoids. A similar infiltrating pattern is also present in the spleen and bone marrow that are usually involved at the time of the diagnosis.

Code History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): Deleted code
  • 2025 (effective 10/1/2024): New code

Diagnosis Index entries containing back-references to C86.1:

  • Lymphoma (of) (malignant) C85.90
    • hepatosplenic T-cell C86.1- (alpha-beta) (gamma-delta)
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