2025 ICD-10-CM Diagnosis Code C86.4

Blastic NK-cell lymphoma

  • C86.4 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • ICD-10-CM C86.4 is a new 2025 ICD-10-CM code that became effective on October 1, 2024.
  • This is the American ICD-10-CM version of C86.4 – other international versions of ICD-10 C86.4 may differ.

Applicable To

  • Blastic plasmacytoid dendritic cell neoplasm (BPDCN)

The following code(s) above C86.4 contain annotation back-references

 that may be applicable to C86.4:

  • C00-D49  Neoplasms
  • C81-C96  Malignant neoplasms of lymphoid, hematopoietic and related tissue
  • C86  Other specified types of T/NK-cell lymphoma

Approximate Synonyms

  • Lymphoma blastic nk-cell

Clinical Information

  • An aggressive immature hematologic neoplasm formerly known as blastic nk cell lymphoma, composed of cells with a lymphoblast-like morphology. Recent evidence suggests derivation from a plasmacytoid dendritic cell precursor. Patients present with cutaneous tumors and disseminated disease.

Code History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): Deleted code
  • 2025 (effective 10/1/2024): New code

Diagnosis Index entries containing back-references to C86.4:

  • Lymphoma (of) (malignant) C85.90
    • blastic NK-cell C86.4-
    • blastic plasmacytoid dendritic cell neoplasm C86.4- (BPDCN)
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