2025 ICD-10-CM Diagnosis Code C86.6

by

Primary cutaneous CD30-positive T-cell proliferations

  • C86.6 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • ICD-10-CM C86.6 is a new 2025 ICD-10-CM code that became effective on October 1, 2024.
  • This is the American ICD-10-CM version of C86.6 – other international versions of ICD-10 C86.6 may differ.

Applicable To

  • Lymphomatoid papulosis
  • Primary cutaneous anaplastic large cell lymphoma
  • Primary cutaneous CD30-positive large T-cell lymphoma

The following code(s) above C86.6 contain annotation back-references

 that may be applicable to C86.6:

  • C00-D49  Neoplasms
  • C81-C96  Malignant neoplasms of lymphoid, hematopoietic and related tissue
  • C86  Other specified types of T/NK-cell lymphoma

Approximate Synonyms

  • Lymphoma, primary cutaneous, large t cell, cd30 po
  • Lymphomatoid papulosis
  • Primary cutaneous cd30+ large t-cell lymphoma

Clinical Information

  • A chronic, recurrent cutaneous disorder characterized by the presence of spontaneously regressing papules. The papules are composed of an atypical lymphocytic infiltrate that contains anaplastic cd30-positive t-cells, which are found in type a and diffuse large cell type (type c) lymphomatoid papulosis. In a small number of cases, of type b, the lymphocytic infiltrate is composed of small, cerebriform-like lymphocytes that are often negative for cd30. The majority of cases follow a benign clinical course, but some cases are clonal and may progress to lymphoma. Treatment options include low dose methotrexate and psoralen/uva (puva).
  • An anaplastic large cell lymphoma limited to the skin at the time of diagnosis. Most patients present with solitary or localized skin lesions, which may be tumors, nodules or papules. The t(2;5) translocation that is present in many cases of systemic anaplastic large cell lymphoma, is not found in this disease. (who, 2001)
  • Anaplastic lymphoma of the skin which develops as a primary neoplasm expressing the cd30 antigen. It is characterized by solitary nodules or ulcerated tumors.
  • Clinically benign, histologically malignant, recurrent cutaneous t-cell lymphoproliferative disorder characterized by an infiltration of large atypical cells surrounded by inflammatory cells. The atypical cells resemble reed-sternberg cells of hodgkin disease or the malignant cells of cutaneous t-cell lymphoma. In some cases, lymphomatoid papulosis progresses to lymphomatous conditions including mycosis fungoides; hodgkin disease; cutaneous t-cell lymphoma; or anaplastic large-cell lymphoma.

Code History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): Deleted code
  • 2025 (effective 10/1/2024): New code

Code annotations containing back-references to C86.6:

Diagnosis Index entries containing back-references to C86.6:

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