2025 ICD-10-CM Diagnosis Code C88.20

Heavy chain disease not having achieved remission

  • C88.20 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • ICD-10-CM C88.20 is a new 2025 ICD-10-CM code that became effective on October 1, 2024.
  • This is the American ICD-10-CM version of C88.20 – other international versions of ICD-10 C88.20 may differ.

Applicable To

  • Franklin disease NOS
  • Franklin disease not having achieved remission
  • Franklin disease with failed remission
  • Gamma heavy chain disease NOS
  • Gamma heavy chain disease not having achieved remission
  • Gamma heavy chain disease with failed remission
  • Heavy chain disease NOS
  • Heavy chain disease with failed remissionMu heavy chain disease not having achieved remission
  • Mu heavy chain disease NOS
  • Mu heavy chain disease not having achieved remission
  • Mu heavy chain disease with failed remission

The following code(s) above C88.20 contain annotation back-references

 that may be applicable to C88.20:

  • C00-D49  Neoplasms
  • C81-C96  Malignant neoplasms of lymphoid, hematopoietic and related tissue
  • C88  Malignant immunoproliferative diseases and certain other B-cell lymphomas
  • C88.2  Heavy chain disease

ICD-10-CM C88.20 is grouped within Diagnostic Related Group(s) (MS-DRG v42.0):

  • 820 Lymphoma and leukemia with major o.r. Procedures with mcc
  • 821 Lymphoma and leukemia with major o.r. Procedures with cc
  • 822 Lymphoma and leukemia with major o.r. Procedures without cc/mcc
  • 823 Lymphoma and non-acute leukemia with other procedures with mcc
  • 824 Lymphoma and non-acute leukemia with other procedures with cc
  • 825 Lymphoma and non-acute leukemia with other procedures without cc/mcc
  • 840 Lymphoma and non-acute leukemia with mcc
  • 841 Lymphoma and non-acute leukemia with cc
  • 842 Lymphoma and non-acute leukemia without cc/mcc

Code History

  • 2025 (effective 10/1/2024): New code
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