2025 ICD-10-CM Diagnosis Code C88.9

by

Malignant immunoproliferative disease, unspecified

  • C88.9 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • ICD-10-CM C88.9 is a new 2025 ICD-10-CM code that became effective on October 1, 2024.
  • This is the American ICD-10-CM version of C88.9 – other international versions of ICD-10 C88.9 may differ.

Applicable To

  • Immunoproliferative disease NOS

The following code(s) above C88.9 contain annotation back-references

 that may be applicable to C88.9:

  • C00-D49  Neoplasms
  • C81-C96  Malignant neoplasms of lymphoid, hematopoietic and related tissue
  • C88  Malignant immunoproliferative diseases and certain other B-cell lymphomas

Approximate Synonyms

  • Immunoproliferative neoplasm
  • Immunoproliferative neoplasm in relapse
  • Immunoproliferative neoplasm in remission
  • Immunoproliferative neoplasm without remission
  • Malignant immunoproliferative disease
  • Malignant immunoproliferative disease (clinical)

Clinical Information

  • Disorders characterized by abnormal proliferation of primary cells of the immune system or by excessive production of immunoglobulins.

Code History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): Deleted code
  • 2025 (effective 10/1/2024): New code

Diagnosis Index entries containing back-references to C88.9:

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