2025 ICD-10-CM Diagnosis Code C96.A

Histiocytic sarcoma

C96.A is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
The 2025 edition of ICD-10-CM C96.A became effective on October 1, 2024.
This is the American ICD-10-CM version of C96.A – other international versions of ICD-10 C96.A may differ.

Applicable To

The following code(s) above C96.A contain annotation back-references

that may be applicable to C96.A:

C00-D49 Neoplasms
C81-C96 Malignant neoplasms of lymphoid, hematopoietic and related tissue
C96 Other and unspecified malignant neoplasms of lymphoid, hematopoietic and related tissue

Approximate Synonyms

Clinical Information

A malignant neoplasm composed of cells resembling histiocytes.
A malignant neoplasm of large lymphocytes, which resemble histiocytes.
A rare, usually progressive disorder comprising an invasive proliferation of neoplastic histiocytes. Many previous cases are now thought to represent anaplastic large-cell lymphoma.
An aggressive malignant neoplasm with a poor response to therapy, usually presenting as stage iii/iv disease. It is characterized by the presence of neoplastic cells with morphologic and immunophenotypic characteristics similar to those seen in mature histiocytes.
An antiquated term referring to cases of systemic non-hodgkin lymphomas which are composed of large, atypical neoplastic lymphoid cells and cases of hemophagocytic syndromes. In the past, cases of anaplastic large cells lymphoma were called malignant histiocytosis.
An antiquated term referring to large cell lymphomas.
An outdated term referring to non-hodgkin lymphomas made up of large abnormal lymphoid cells. Histiocytic lymphomas include mature b-cell and t-cell non-hodgkin lymphomas. Many tumors that were once called histiocytic lymphomas are now considered to be a type of large cell lymphoma.
Malignant neoplasms composed of macrophages or dendritic cells. Most histiocytic sarcomas present as localized tumor masses without a leukemic phase. Though the biological behavior of these neoplasms resemble lymphomas, their cell lineage is histiocytic not lymphoid.

ICD-10-CM C96.A is grouped within Diagnostic Related Group(s) (MS-DRG v42.0):

011 Tracheostomy for face, mouth and neck diagnoses or laryngectomy with mcc
012 Tracheostomy for face, mouth and neck diagnoses or laryngectomy with cc
013 Tracheostomy for face, mouth and neck diagnoses or laryngectomy without cc/mcc
820 Lymphoma and leukemia with major o.r. Procedures with mcc
821 Lymphoma and leukemia with major o.r. Procedures with cc
822 Lymphoma and leukemia with major o.r. Procedures without cc/mcc
823 Lymphoma and non-acute leukemia with other procedures with mcc
824 Lymphoma and non-acute leukemia with other procedures with cc
825 Lymphoma and non-acute leukemia with other procedures without cc/mcc
840 Lymphoma and non-acute leukemia with mcc
841 Lymphoma and non-acute leukemia with cc
842 Lymphoma and non-acute leukemia without cc/mcc

Convert C96.A to ICD-9-CMCode History

2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
2017 (effective 10/1/2016): No change
2018 (effective 10/1/2017): No change
2019 (effective 10/1/2018): No change
2020 (effective 10/1/2019): No change
2021 (effective 10/1/2020): No change
2022 (effective 10/1/2021): No change
2023 (effective 10/1/2022): No change
2024 (effective 10/1/2023): No change
2025 (effective 10/1/2024): No change

Code annotations containing back-references to C96.A:

Diagnosis Index entries containing back-references to C96.A:

ArthropathyM12.9 – see also Arthritis
- in (due to)
  - malignant histiocytosis C96.A
HistiocytosisD76.3
- malignant C96.A
Lymphoma (of) (malignant) C85.90
- histiocyticC85.9-
  - true C96.A
- true histiocytic C96.A
Reticulosis (skin)
- histiocytic medullary C96.A
Sarcoma (of) – see also Neoplasm, connective tissue, malignant
- histiocytic C96.A