2025 ICD-10-CM Diagnosis Code E05.21

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Thyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis or storm

  • E05.21 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • Short description: Thyrotxcosis w toxic multinodular goiter w thyrotoxic crisis
  • The 2025 edition of ICD-10-CM E05.21 became effective on October 1, 2024.
  • This is the American ICD-10-CM version of E05.21 – other international versions of ICD-10 E05.21 may differ.

The following code(s) above E05.21 contain annotation back-references

 that may be applicable to E05.21:

  • E00-E89  Endocrine, nutritional and metabolic diseases
  • E05  Thyrotoxicosis [hyperthyroidism]
  • E05.2  Thyrotoxicosis with toxic multinodular goiter

Approximate Synonyms

  • Thyroid goiter, toxic, nodular, with crisis
  • Toxic multinodular goiter with thyrotoxic crisis
  • Toxic multinodular thyroid goiter, thyrotoxic crisis
  • Toxic nodular goiter with thyrotoxic storm

ICD-10-CM E05.21 is grouped within Diagnostic Related Group(s) (MS-DRG v42.0):

  • 011 Tracheostomy for face, mouth and neck diagnoses or laryngectomy with mcc
  • 012 Tracheostomy for face, mouth and neck diagnoses or laryngectomy with cc
  • 013 Tracheostomy for face, mouth and neck diagnoses or laryngectomy without cc/mcc
  • 643 Endocrine disorders with mcc
  • 644 Endocrine disorders with cc
  • 645 Endocrine disorders without cc/mcc

Convert E05.21 to ICD-9-CMCode History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): No change

Diagnosis Index entries containing back-references to E05.21:

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