2025 ICD-10-CM Diagnosis Code E16.0

Drug-induced hypoglycemia without coma

  • E16.0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2025 edition of ICD-10-CM E16.0 became effective on October 1, 2024.
  • This is the American ICD-10-CM version of E16.0 – other international versions of ICD-10 E16.0 may differ.

Use Additional

  • code for adverse effect, if applicable, to identify drug (T36-T50  with fifth or sixth character 5)

Type 1 Excludes

  • diabetes with hypoglycemia without coma (E09.649)

The following code(s) above E16.0 contain annotation back-references

 that may be applicable to E16.0:

  • E00-E89  Endocrine, nutritional and metabolic diseases

Approximate Synonyms

  • Drug induced hypoglycemia

ICD-10-CM E16.0 is grouped within Diagnostic Related Group(s) (MS-DRG v42.0):

  • 643 Endocrine disorders with mcc
  • 644 Endocrine disorders with cc
  • 645 Endocrine disorders without cc/mcc

Convert E16.0 to ICD-9-CMCode History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): No change

Diagnosis Index entries containing back-references to E16.0:

  • Hypoglycemia (spontaneous) E16.2
    • drug-induced E16.0
    • due to insulin E16.0
    • iatrogenic E16.0
  • Reaction – see also Disorder
    • hypoglycemic, due to insulin E16.0
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