2025 ICD-10-CM Diagnosis Code E22

by

Hyperfunction of pituitary gland

  • E22 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2025 edition of ICD-10-CM E22 became effective on October 1, 2024.
  • This is the American ICD-10-CM version of E22 – other international versions of ICD-10 E22 may differ.

Type 1 Excludes

  • Cushing’s syndrome (E24.-)
  • Nelson’s syndrome (E24.1)
  • overproduction of ACTH not associated with Cushing’s disease (E27.0)
  • overproduction of pituitary ACTH (E24.0)
  • overproduction of thyroid-stimulating hormone (E05.8-)

The following code(s) above E22 contain annotation back-references

 that may be applicable to E22:

  • E00-E89  Endocrine, nutritional and metabolic diseases
  • E20-E35  Disorders of other endocrine glands

Code History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): No change
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