2025 ICD-10-CM Diagnosis Code E24.0

Pituitary-dependent Cushing’s disease

• E24.0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
• The 2025 edition of ICD-10-CM E24.0 became effective on October 1, 2024.
• This is the American ICD-10-CM version of E24.0 – other international versions of ICD-10 E24.0 may differ.

Applicable To

• Overproduction of pituitary ACTH
• Pituitary-dependent hypercorticalism

The following code(s) above E24.0 contain annotation back-references

 that may be applicable to E24.0:

• E00-E89  Endocrine, nutritional and metabolic diseases
• E20-E35  Disorders of other endocrine glands
• E24  Cushing’s syndrome

Approximate Synonyms

• Cushing disease
• Pituitary dependent hypercortisolism

Clinical Information

• A disease of the pituitary gland characterized by the excess amount of adrenocorticotropic hormone secreted. This leads to hypersecretion of cortisol (hydrocortisone) by the adrenal glands resulting in cushing syndrome.

ICD-10-CM E24.0 is grouped within Diagnostic Related Group(s) (MS-DRG v42.0):

• 643 Endocrine disorders with mcc
• 644 Endocrine disorders with cc
• 645 Endocrine disorders without cc/mcc

Convert E24.0 to ICD-9-CMCode History

• 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
• 2017 (effective 10/1/2016): No change
• 2018 (effective 10/1/2017): No change
• 2019 (effective 10/1/2018): No change
• 2020 (effective 10/1/2019): No change
• 2021 (effective 10/1/2020): No change
• 2022 (effective 10/1/2021): No change
• 2023 (effective 10/1/2022): No change
• 2024 (effective 10/1/2023): No change
• 2025 (effective 10/1/2024): No change

Code annotations containing back-references to E24.0:

• Type 1 Excludes: E22

Diagnosis Index entries containing back-references to E24.0:

• Basophilism E24.0 (cortico-adrenal) (Cushing’s) (pituitary)
• Cushing’s
  • syndrome or diseaseE24.9
    • pituitary-dependent E24.0
• HyperadrenocorticismE24.9
  • pituitary-dependent E24.0
• Hypercorticalism, pituitary-dependent E24.0
• Hypersecretion
  • ACTH (not associated with Cushing’s syndrome) E27.0
    • pituitary E24.0
  • hormone(s)
    • ACTH (not associated with Cushing’s syndrome) E27.0
      • pituitary E24.0
• Syndrome – see also Disease
  • Cushing’sE24.9
    • due to
      • overproduction of pituitary ACTH E24.0
    • pituitary-dependent E24.0