2025 ICD-10-CM Diagnosis Code E27.0

Other adrenocortical overactivity

• E27.0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
• The 2025 edition of ICD-10-CM E27.0 became effective on October 1, 2024.
• This is the American ICD-10-CM version of E27.0 – other international versions of ICD-10 E27.0 may differ.

Applicable To

• Overproduction of ACTH, not associated with Cushing’s disease
• Premature adrenarche

Type 1 Excludes

• Cushing’s syndrome (E24.-)

The following code(s) above E27.0 contain annotation back-references

 that may be applicable to E27.0:

• E00-E89  Endocrine, nutritional and metabolic diseases
• E20-E35  Disorders of other endocrine glands

Approximate Synonyms

• Acquired benign adrenal androgenic overactivity
• Adrenal androgenic overactivity, acquired benign
• Premature adrenarche
• Premature adrenarche (puberty disorder)

ICD-10-CM E27.0 is grouped within Diagnostic Related Group(s) (MS-DRG v42.0):

• 643 Endocrine disorders with mcc
• 644 Endocrine disorders with cc
• 645 Endocrine disorders without cc/mcc

Convert E27.0 to ICD-9-CMCode History

• 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
• 2017 (effective 10/1/2016): No change
• 2018 (effective 10/1/2017): No change
• 2019 (effective 10/1/2018): No change
• 2020 (effective 10/1/2019): No change
• 2021 (effective 10/1/2020): No change
• 2022 (effective 10/1/2021): No change
• 2023 (effective 10/1/2022): No change
• 2024 (effective 10/1/2023): No change
• 2025 (effective 10/1/2024): No change

Code annotations containing back-references to E27.0:

• Type 1 Excludes: E22

Diagnosis Index entries containing back-references to E27.0:

• Adrenarche, premature E27.0
• Disease, diseased – see also Syndrome
  • adrenal (capsule) (cortex) (gland) (medullary) E27.9
    • hyperfunction E27.0
  • suprarenal (capsule) (gland) E27.9
    • hyperfunction E27.0
• DysadrenocortismE27.9
  • hyperfunction E27.0
• Dysfunction
  • adrenalE27.9
    • hyperfunction E27.0
  • suprarenalE27.9
    • hyperfunction E27.0
• HyperadrenocorticismE24.9
  • not associated with Cushing’s syndrome E27.0
• Hyperfunction
  • adrenal cortex, not associated with Cushing’s syndrome E27.0
• Hypersecretion
  • ACTH (not associated with Cushing’s syndrome) E27.0
  • hormone(s)
    • ACTH (not associated with Cushing’s syndrome) E27.0
• Overactive – see also Hyperfunction
  • adrenal cortex NEC E27.0
• Overproduction – see also Hypersecretion
  • ACTH E27.0
• Premature – see also condition
  • adrenarche E27.0
• Schroeder’s syndrome E27.0 (endocrine hypertensive)
• Slocumb’s syndrome E27.0
• Syndrome – see also Disease
  • endocrine-hypertensive E27.0
  • Schroeder’s E27.0
  • Slocumb’s E27.0
  • suprarenal cortical E27.0