2025 ICD-10-CM Diagnosis Code E28.0

Estrogen excess

  • E28.0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2025 edition of ICD-10-CM E28.0 became effective on October 1, 2024.
  • This is the American ICD-10-CM version of E28.0 – other international versions of ICD-10 E28.0 may differ.

ICD-10-CM Coding Rules

  • E28.0 is applicable to female patients.

Use Additional

  • code for adverse effect, if applicable, to identify drug (T36-T50  with fifth or sixth character 5)

The following code(s) above E28.0 contain annotation back-references

 that may be applicable to E28.0:

  • E00-E89  Endocrine, nutritional and metabolic diseases
  • E20-E35  Disorders of other endocrine glands
  • E28  Ovarian dysfunction

Approximate Synonyms

  • Hyperestrogenism

ICD-10-CM E28.0 is grouped within Diagnostic Related Group(s) (MS-DRG v42.0):

  • 742 Uterine and adnexa procedures for non-malignancy with cc/mcc
  • 743 Uterine and adnexa procedures for non-malignancy without cc/mcc
  • 760 Menstrual and other female reproductive system disorders with cc/mcc
  • 761 Menstrual and other female reproductive system disorders without cc/mcc

Convert E28.0 to ICD-9-CMCode History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): No change

Diagnosis Index entries containing back-references to E28.0:

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