2025 ICD-10-CM Diagnosis Code E43

Unspecified severe protein-calorie malnutrition

• E43 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
• The 2025 edition of ICD-10-CM E43 became effective on October 1, 2024.
• This is the American ICD-10-CM version of E43 – other international versions of ICD-10 E43 may differ.

Applicable To

• Starvation edema

The following code(s) above E43 contain annotation back-references

 that may be applicable to E43:

• E00-E89  Endocrine, nutritional and metabolic diseases
• E40-E46  Malnutrition

Approximate Synonyms

• Diabetes type 1 with severe malnutrition
• Diabetes type 2 with severe malnutrition
• Edema due to nutritional deficiency
• Nutritional edema
• Protein calorie malnutrition, severe
• Severe malnutrition due to type 1 diabetes mellitus
• Severe malnutrition due to type 2 diabetes mellitus
• Severe protein-calorie malnutrition (gomez: less than 60% of standard weight)

ICD-10-CM E43 is grouped within Diagnostic Related Group(s) (MS-DRG v42.0):

• 640 Miscellaneous disorders of nutrition, metabolism, fluids and electrolytes with mcc
• 641 Miscellaneous disorders of nutrition, metabolism, fluids and electrolytes without mcc
• 791 Prematurity with major problems
• 793 Full term neonate with major problems

Convert E43 to ICD-9-CMCode History

• 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
• 2017 (effective 10/1/2016): No change
• 2018 (effective 10/1/2017): No change
• 2019 (effective 10/1/2018): No change
• 2020 (effective 10/1/2019): No change
• 2021 (effective 10/1/2020): No change
• 2022 (effective 10/1/2021): No change
• 2023 (effective 10/1/2022): No change
• 2024 (effective 10/1/2023): No change
• 2025 (effective 10/1/2024): No change

Code annotations containing back-references to E43:

• Note: E64

Diagnosis Index entries containing back-references to E43:

• AnasarcaR60.1
  • nutritional E43
• Atrophy, atrophic (of)
  • nutritional E43
• Deficiency, deficient
  • calorie, severe E43
• Disease, diseased – see also Syndrome
  • wasting NECE88.A
    • due to
      • malnutrition E43
• EmaciationR64
  • due to malnutrition E43
• MalnutritionE46
  • degree
    • severe (protein-energy) E43
    • third E43
  • proteinE46
    • calorieE46
      • severe E43
    • energyE46
      • severe E43
  • severe (protein-energy) E43
• Wasting
  • disease (syndrome) E88.A
    • due to
      • malnutrition E43
  • extreme (due to malnutrition) E43