Disorders of plasma-protein metabolism, not elsewhere classified
- E88.0 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
- Short description: Disorders of plasma-protein metabolism, NEC
- The 2025 edition of ICD-10-CM E88.0 became effective on October 1, 2024.
- This is the American ICD-10-CM version of E88.0 – other international versions of ICD-10 E88.0 may differ.
Type 1 Excludes
- monoclonal gammopathy (of undetermined significance) (D47.2)
- polyclonal hypergammaglobulinemia (D89.0)
- Waldenström macroglobulinemia (C88.00)
Type 2 Excludes
- disorder of lipoprotein metabolism (E78.-)
The following code(s) above E88.0 contain annotation back-references
that may be applicable to E88.0:
- E00-E89 Endocrine, nutritional and metabolic diseases
- E70-E88 Metabolic disorders
- E88 Other and unspecified metabolic disorders
Code History
- 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
- 2017 (effective 10/1/2016): No change
- 2018 (effective 10/1/2017): No change
- 2019 (effective 10/1/2018): No change
- 2020 (effective 10/1/2019): No change
- 2021 (effective 10/1/2020): No change
- 2022 (effective 10/1/2021): No change
- 2023 (effective 10/1/2022): No change
- 2024 (effective 10/1/2023): No change
- 2025 (effective 10/1/2024): No change
Code annotations containing back-references to E88.0:
- Type 1 Excludes: R77