2025 ICD-10-CM Diagnosis Code F21

Schizotypal disorder

• F21 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
• The 2025 edition of ICD-10-CM F21 became effective on October 1, 2024.
• This is the American ICD-10-CM version of F21 – other international versions of ICD-10 F21 may differ.

Applicable To

• Borderline schizophrenia
• Latent schizophrenia
• Latent schizophrenic reaction
• Prepsychotic schizophrenia
• Prodromal schizophrenia
• Pseudoneurotic schizophrenia
• Pseudopsychopathic schizophrenia
• Schizotypal personality disorder

Type 2 Excludes

• Asperger’s syndrome (F84.5)
• schizoid personality disorder (F60.1)

The following code(s) above F21 contain annotation back-references

 that may be applicable to F21:

• F01-F99  Mental, Behavioral and Neurodevelopmental disorders

Approximate Synonyms

• Acute exacerbation of chronic latent schizophrenia
• Acute exacerbation of subchronic latent schizophrenia
• Chronic latent schizophrenia
• Latent schizophrenia
• Latent schizophrenia in remission
• Schizophrenia, latent
• Schizophrenia, latent, chronic
• Schizophrenia, latent, chronic, acute exacerbation
• Schizophrenia, latent, in remission
• Schizophrenia, latent, subchronic
• Schizophrenia, latent, subchronic, acute exacerbation
• Schizotypal personality disorder
• Subchronic latent schizophrenia

Clinical Information

• A disorder characterized by an enduring pattern of inability to establish close relationships coupled with cognitive or perceptual distortions, odd beliefs and speech, and eccentric behavior and appearance.
• A personality disorder in which there are oddities of thought (magical thinking, paranoid ideation, suspiciousness), perception (illusions, depersonalization), speech (digressive, vague, overelaborate), and behavior (inappropriate affect in social interactions, frequently social isolation) that are not severe enough to characterize schizophrenia.
• Personality disorder characterized by eccentric thoughts and appearance, inappropriate affect and behavior, extreme social anxiety, and limited interpersonal interaction.

ICD-10-CM F21 is grouped within Diagnostic Related Group(s) (MS-DRG v42.0):

• 883 Disorders of personality and impulse control

Convert F21 to ICD-9-CMCode History

• 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
• 2017 (effective 10/1/2016): No change
• 2018 (effective 10/1/2017): No change
• 2019 (effective 10/1/2018): No change
• 2020 (effective 10/1/2019): No change
• 2021 (effective 10/1/2020): No change
• 2022 (effective 10/1/2021): No change
• 2023 (effective 10/1/2022): No change
• 2024 (effective 10/1/2023): No change
• 2025 (effective 10/1/2024): No change

Code annotations containing back-references to F21:

• Type 2 Excludes: F20, F60.1

Diagnosis Index entries containing back-references to F21:

• Disorder (of) – see also Disease
  • personalityF60.9 – see also Personality
    • schizotypal F21
  • schizotypal F21 (personality)
• Reaction – see also Disorder
  • schizophrenicF23
    • latent F21
• Schizophrenia, schizophrenicF20.9
  • borderline F21
  • incipient F21
  • latent F21
  • prepsychotic F21
  • prodromal F21
  • pseudoneurotic F21
  • pseudopsychopathic F21