2025 ICD-10-CM Diagnosis Code I21.9

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Acute myocardial infarction, unspecified

  • I21.9 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2025 edition of ICD-10-CM I21.9 became effective on October 1, 2024.
  • This is the American ICD-10-CM version of I21.9 – other international versions of ICD-10 I21.9 may differ.

Applicable To

  • Myocardial infarction (acute) NOS

The following code(s) above I21.9 contain annotation back-references

 that may be applicable to I21.9:

  • I00-I99  Diseases of the circulatory system
  • I20-I25  Ischemic heart diseases
  • I21  Acute myocardial infarction

Clinical Information

  • Necrosis of the myocardium, as a result of interruption of the blood supply to the area. It is characterized by a severe and rapid onset of symptoms that may include chest pain, often radiating to the left arm and left side of the neck, dyspnea, sweating, and palpitations.

ICD-10-CM I21.9 is grouped within Diagnostic Related Group(s) (MS-DRG v42.0):

  • 280 Acute myocardial infarction, discharged alive with mcc
  • 281 Acute myocardial infarction, discharged alive with cc
  • 282 Acute myocardial infarction, discharged alive without cc/mcc
  • 283 Acute myocardial infarction, expired with mcc
  • 284 Acute myocardial infarction, expired with cc
  • 285 Acute myocardial infarction, expired without cc/mcc

Convert I21.9 to ICD-9-CMCode History

  • 2018 (effective 10/1/2017): New code
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): No change

Diagnosis Index entries containing back-references to I21.9:

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