2025 ICD-10-CM Diagnosis Code I22

by

Subsequent ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction

  • I22 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • Short description: Subsequent STEMI & NSTEMI mocard infrc
  • The 2025 edition of ICD-10-CM I22 became effective on October 1, 2024.
  • This is the American ICD-10-CM version of I22 – other international versions of ICD-10 I22 may differ.

Use Additional

  • code, if applicable, to identify:
  • exposure to environmental tobacco smoke (Z77.22)
  • history of tobacco dependence (Z87.891)
  • occupational exposure to environmental tobacco smoke (Z57.31)
  • status post administration of tPA (rtPA) in a different facility within the last 24 hours prior to admission to current facility (Z92.82)
  • tobacco dependence (F17.-)
  • tobacco use (Z72.0)

Type 1 Excludes

  • subsequent myocardial infarction, type 2 (I21.A1)
  • subsequent myocardial infarction of other type (type 3) (type 4) (type 5) (I21.A9)

Includes

  • acute myocardial infarction occurring within four weeks (28 days) of a previous acute myocardial infarction, regardless of site
  • cardiac infarction
  • coronary (artery) embolism
  • coronary (artery) occlusion
  • coronary (artery) rupture
  • coronary (artery) thrombosis
  • infarction of heart, myocardium, or ventricle
  • recurrent myocardial infarction
  • reinfarction of myocardium
  • rupture of heart, myocardium, or ventricle
  • subsequent type 1 myocardial infarction

The following code(s) above I22 contain annotation back-references

 that may be applicable to I22:

  • I00-I99  Diseases of the circulatory system
  • I20-I25  Ischemic heart diseases

Clinical Information

  • A disorder characterized by gross necrosis of the myocardium; this is due to an interruption of blood supply to the area.
  • Coagulation of blood in any of the coronary vessels. The presence of a blood clot (thrombus) often leads to myocardial infarction.
  • Complete blockage of blood flow through one of the coronary arteries, usually from coronary atherosclerosis.
  • Each year over a million people in the United States Have a heart attack. About half of them die. Many people have permanent heart damage or die because they don’t get help immediately. It’s important to know the symptoms of a heart attack and call 9-1-1 if someone is having them. Those symptoms include
    • chest discomfort – pressure, squeezing, or pain
    • shortness of breath
    • discomfort in the upper body – arms, shoulder, neck, back
    • nausea, vomiting, dizziness, lightheadedness, sweating
    these symptoms can sometimes be different in women.what exactly is a heart attack? most heart attacks happen when a clot in the coronary artery blocks the supply of blood and oxygen to the heart. Often this leads to an irregular heartbeat – called an arrhythmia – that causes a severe decrease in the pumping function of the heart. A blockage that is not treated within a few hours causes the affected heart muscle to die.
  • Gross necrosis of the myocardium, as a result of interruption of the blood supply to the area, as in coronary thrombosis.
  • Gross necrosis of the myocardium, as a result of interruption of the blood supply to the area.
  • Necrosis of the myocardium caused by an obstruction of the blood supply to the heart (coronary circulation).

Code History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): No change

Code annotations containing back-references to I22:

  • Code First: Z92.82
  • Type 1 Excludes: I25.82
  • Type 2 Excludes: I21
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