2025 ICD-10-CM Diagnosis Code I25.81

Atherosclerosis of other coronary vessels without angina pectoris

  • I25.81 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • Short description: Atherosclerosis of oth coronary vessels w/o angina pectoris
  • The 2025 edition of ICD-10-CM I25.81 became effective on October 1, 2024.
  • This is the American ICD-10-CM version of I25.81 – other international versions of ICD-10 I25.81 may differ.

Use Additional

  • code, if applicable, to identify:
  • coronary atherosclerosis due to calcified coronary lesion (I25.84)
  • coronary atherosclerosis due to lipid rich plaque (I25.83)

Type 2 Excludes

  • atherosclerotic heart disease of native coronary artery without angina pectoris (I25.10)

The following code(s) above I25.81 contain annotation back-references

 that may be applicable to I25.81:

  • I00-I99  Diseases of the circulatory system
  • I20-I25  Ischemic heart diseases
  • I25  Chronic ischemic heart disease

Code History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): No change

Code annotations containing back-references to I25.81:

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