2025 ICD-10-CM Diagnosis Code I45.81

Long QT syndrome

  • I45.81 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2025 edition of ICD-10-CM I45.81 became effective on October 1, 2024.
  • This is the American ICD-10-CM version of I45.81 – other international versions of ICD-10 I45.81 may differ.

The following code(s) above I45.81 contain annotation back-references

 that may be applicable to I45.81:

  • I00-I99  Diseases of the circulatory system

Approximate Synonyms

  • Acquired long qt syndrome
  • Acquired long qt syndrome (heart)
  • Congenital long qt syndrome
  • Congenital long qt syndrome (at birth)
  • Prolonged qt interval syndrome
  • Torsades de pointes
  • Torsades type ventricular tachycardia

Clinical Information

  • A condition that is characterized by episodes of fainting (syncope) and varying degree of ventricular arrhythmia as indicated by the prolonged qt interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are romano-ward syndrome and jervell-lange nielsen syndrome.
  • A ventricular arrhythmia characterized by syncopal episodes and a long qt interval, sometimes leading to sudden death due to paroxysmal ventricular arrhythmia. This arrhythmia is associated with a prolongation of repolarization following depolarization of the cardiac ventricles. The prolongation of the q-t interval combined with torsades de pointes manifests as several different forms; some may be acquired or congenital; some may lead to serious arrhythmia and sudden cardiac death.
  • Prolongation of q-t interval combined with torsades de pointes and manifests as several different forms; may be acquired or congenital; may lead to serious arrhythmia and sudden cardiac death.

ICD-10-CM I45.81 is grouped within Diagnostic Related Group(s) (MS-DRG v42.0):

  • 308 Cardiac arrhythmia and conduction disorders with mcc
  • 309 Cardiac arrhythmia and conduction disorders with cc
  • 310 Cardiac arrhythmia and conduction disorders without cc/mcc

Convert I45.81 to ICD-9-CMCode History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): No change

Code annotations containing back-references to I45.81:

  • Code Also: I47.21
  • Type 1 Excludes: R94.31

Diagnosis Index entries containing back-references to I45.81:

  • Jervell-Lange-Nielsen syndrome I45.81
  • Long
    • QT syndrome I45.81
  • Romano-Ward I45.81 (prolonged QT interval)
  • Syndrome – see also Disease
    • Jervell-Lange-Nielsen I45.81
    • long QT I45.81
    • QT interval prolongation I45.81
    • Romano-Ward I45.81 (prolonged QT interval)
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