2025 ICD-10-CM Diagnosis Code I51.5

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Myocardial degeneration

  • I51.5 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2025 edition of ICD-10-CM I51.5 became effective on October 1, 2024.
  • This is the American ICD-10-CM version of I51.5 – other international versions of ICD-10 I51.5 may differ.

Applicable To

  • Fatty degeneration of heart or myocardium
  • Myocardial disease
  • Senile degeneration of heart or myocardium

The following code(s) above I51.5 contain annotation back-references

 that may be applicable to I51.5:

  • I00-I99  Diseases of the circulatory system
  • I51  Complications and ill-defined descriptions of heart disease

Approximate Synonyms

  • Fatty degeneration of heart

Clinical Information

  • A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.
  • A group of diseases in which the dominant feature is the involvement of the cardiac muscle itself. Cardiomyopathies are classified according to their predominant pathophysiological features (dilated cardiomyopathy; hypertrophic cardiomyopathy; restrictive cardiomyopathy) or their etiological/pathological factors (cardiomyopathy, alcoholic; endocardial fibroelastosis).
  • Cardiomyopathy refers to diseases of the heart muscle. These diseases enlarge your heart muscle or make it thicker and more rigid than normal. In rare cases, scar tissue replaces the muscle tissue.some people live long, healthy lives with cardiomyopathy. Some people don’t even realize they have it. In others, however, it can make the heart less able to pump blood through the body. This can cause serious complications, including
    • heart failure
    • abnormal heart rhythms
    • fluid buildup in your lungs or legs
    • endocarditis, an inflammation of the heart lining
    heart attacks, high blood pressure or infections can all cause cardiomyopathy. Some types of cardiomyopathy run in families. In many people, however, the cause is unknown. Treatment might involve medicines, surgery, other medical procedures and lifestyle changes.
  • Condition in which there is a deviation from or interruption of the normal structure or function of the myocardium, the middle and thickest layer of the heart wall, composed of heart muscle.

ICD-10-CM I51.5 is grouped within Diagnostic Related Group(s) (MS-DRG v42.0):

  • 314 Other circulatory system diagnoses with mcc
  • 315 Other circulatory system diagnoses with cc
  • 316 Other circulatory system diagnoses without cc/mcc

Convert I51.5 to ICD-9-CMCode History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): No change

Diagnosis Index entries containing back-references to I51.5:

  • Cardiomalacia I51.5
  • Cardiomyoliposis I51.5
  • Degeneration, degenerative
    • myocardial, myocardium (fatty) (hyaline) (senile) I51.5
  • Disease, diseased – see also Syndrome
    • myocardium, myocardial I51.5 – see also Degeneration, myocardial
  • Myocytolysis I51.5
  • Stricture – see also Stenosis
    • myocardium, myocardial I51.5
  • Syndrome – see also Disease
    • Beau’s I51.5
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