2025 ICD-10-CM Diagnosis Code C83.390

Primary central nervous system lymphoma

  • C83.390 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • ICD-10-CM C83.390 is a new 2025 ICD-10-CM code that became effective on October 1, 2024.
  • This is the American ICD-10-CM version of C83.390 – other international versions of ICD-10 C83.390 may differ.

Applicable To

  • PCNSL of brain
  • PCNSL of meninges
  • PCNSL of spinal cord
  • PCNSL NOS

Type 1 Excludes

  • Primary central nervous system lymphoma, Burkitt (C83.79)
  • Primary central nervous system lymphoma, lymphoblastic (C83.59)
  • Primary central nervous system lymphoma, other (C83.89)
  • Primary central nervous system lymphoma, peripheral T-cell (C84.49)

The following code(s) above C83.390 contain annotation back-references

 that may be applicable to C83.390:

  • C00-D49  Neoplasms
  • C81-C96  Malignant neoplasms of lymphoid, hematopoietic and related tissue
  • C83  Non-follicular lymphoma
  • C83.3  Diffuse large B-cell lymphoma

ICD-10-CM C83.390 is grouped within Diagnostic Related Group(s) (MS-DRG v42.0):

  • 820 Lymphoma and leukemia with major o.r. Procedures with mcc
  • 821 Lymphoma and leukemia with major o.r. Procedures with cc
  • 822 Lymphoma and leukemia with major o.r. Procedures without cc/mcc
  • 823 Lymphoma and non-acute leukemia with other procedures with mcc
  • 824 Lymphoma and non-acute leukemia with other procedures with cc
  • 825 Lymphoma and non-acute leukemia with other procedures without cc/mcc
  • 840 Lymphoma and non-acute leukemia with mcc
  • 841 Lymphoma and non-acute leukemia with cc
  • 842 Lymphoma and non-acute leukemia without cc/mcc
  • 974 Hiv with major related condition with mcc
  • 975 Hiv with major related condition with cc
  • 976 Hiv with major related condition without cc/mcc

Code History

  • 2025 (effective 10/1/2024): New code

Diagnosis Index entries containing back-references to C83.390:

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