Macrocytic Anemia ICD-10: A Comprehensive Guide

In this article, we provide a detailed overview of macrocytic anemia and its classification under the ICD-10 coding system. Explore the causes, symptoms, diagnostic criteria, and treatment options for this condition.

Macrocytic anemia is a type of anemia characterized by abnormally large red blood cells (RBCs) in the bloodstream. It is classified under the International Classification of Diseases, Tenth Revision (ICD-10) coding system. Understanding the ICD-10 classification for macrocytic anemia is essential for accurate diagnosis and appropriate management.

In this comprehensive guide, we will delve into the details of macrocytic anemia, its ICD-10 codes, and provide valuable insights into its causes, symptoms, diagnostic criteria, and treatment options.

Macrocytic Anemia ICD-10 Codes

Under the ICD-10 coding system, macrocytic anemia falls under the broader category of “Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism” (Chapter III). Specifically, macrocytic anemia is categorized under “Anemias” (Section D50-D64). Let’s explore the relevant ICD-10 codes associated with macrocytic anemia:

D51 – Vitamin B12 Deficiency Anemia

ICD-10 code D51 is specifically used for vitamin B12 deficiency anemia, which is a common cause of macrocytic anemia. This code is further classified into subcategories based on the severity and clinical manifestations of the condition. Some of the subcategories include:

  1. D51.0 – Vitamin B12 deficiency anemia due to intrinsic factor deficiency: This code is used when the anemia is caused by a lack of intrinsic factor, a protein necessary for the absorption of vitamin B12.
  2. D51.1 – Vitamin B12 deficiency anemia due to selective vitamin B12 malabsorption with proteinuria: This code is applicable when the anemia results from selective vitamin B12 malabsorption accompanied by proteinuria, a condition where excess protein is excreted in the urine.
  3. D51.2 – Transcobalamin II deficiency: This code is assigned when the anemia is caused by a deficiency of transcobalamin II, a protein responsible for the transport of vitamin B12.

D52 – Folate Deficiency Anemia

ICD-10 code D52 is used for folate deficiency anemia, another common cause of macrocytic anemia. This code is also further divided into subcategories based on the severity and clinical manifestations of the condition. Some of the subcategories include:

  1. D52.0 – Dietary folate deficiency anemia: This code is utilized when the anemia is due to inadequate dietary intake of folate, a B-vitamin essential for red blood cell production.
  2. D52.1 – Drug-induced folate deficiency anemia: This code is assigned when the anemia is caused by the use of certain medications that interfere with folate metabolism or absorption.
  3. D52.2 – Folate deficiency anemia due to alcoholism: This code is applicable when the anemia is a result of chronic alcohol abuse leading to inadequate folate levels.
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